GLP Phys-chem

Equipped with state-of-the-art sophisticated instruments, JDM Research offers analytical services in compliance with national and international guidelines such as OECD, USEPA, OPPTS, SANCO (SANTE), APVMA, ABNT NBR, BIS, CIPAC, ASTM, EEC, FAO, WHO, REACH, IP, BP, USP, JP, USFDA, ICH, Schedule Y, RCGM, etc. suited to customer needs.

Services offered

  • Five-batch Analysis
  • Assay and Impurity quantification by 3D analysis
  • Phys-Chem Studies (> 50 parameters) for Technical and Formulation Product
  • Organic Volatile Impurity analysis
  • Stability Studies
  • Method Development and Validation
  • Impurity Isolation/ Standard Preparation
  • Characterization by GC-MS/MS, LC-MS/MS, FT-IR, UV & NMR / DSC

Facilities

Instrument LabInstrument Lab
Characterization lab
Wet Lab
Stability Lab

Equipment

GC (FID, TCD, ECD, FPD Detectors)
HPLC (UV, RID, PDA Detectors)
UV-VIS Spectrophotometer
GC-MS/MS triple quadrupole with Head space
LC-MS/MS triple quadrupole
Particle size analyser (Wet/Dry mode)
Surfacetensiometer
Viscometer
Melting Point / Boiling Point Apparatus
Differential Scanning Calorimeter (DSC)
Thermo-Gravimetric Analyzer (TGA)
FT-IR

Detail list of Studies

PC-01 Analytical Method Validation
PC-02 UV-VIS Absorption Spectra
PC-03 Melting Point/ Range
PC-04 Boiling Point / Range
PC-05 Vapour Pressure by TGA
PC-06 Water Solubility
PC-07 Partition Coefficient
PC-08 Density, Bulk Density, Specific Gravity and Relative Density
PC-09 Particle Size Analysis by Laser Diffraction
PC-10 Hydrolysis as a Function of pH
PC-11 Dissociation Constants in Water by UV Method
PC-12 Screening Test for Thermal Stability and Stability in Air
PC-13 Surface Tension
PC-14 pH, Acidity or Alkalinity
PC-15 Appereance ( Colour,Odor and Physical State)
PC-16 Explosive Property (Explodability) By DSC
PC-17 Spectra Analysis (IR, UV and Mass) NMR
PC-18 Stability to Normal and Elevated Temperatures, Metal and Metal Ions
PC-19 Moisture (by KF)
PC-20 Material Insoluble in Acetone
PC-21 Loss On Drying
PC-22 Sulphated Ash
PC-23 Flash Point
PC-24 Acclerate Storage Stability and Corrosion Characetristics
PC-25 Self Life of Sample (1 Year / 2 years / 3 Years)
PC-26 Oxidising Property for Solid
PC-27 Flammability for Solid
PC-28 AI Content
PC-29 Viscosity of Liquids
PC-30 Chemical Imcompatibility (Oxidation/ Reduction)
PC-31 Corrossive Property
PC-32 Solubility in Organic Solvents
PC-33 Freezing (Low) Temperature
PC-34 Emulsion Stability
PC-35 Persistent Foam
PC-36 Pourability
PC-37 Miscibility
PC-38 Container Compatibility
PC-39 Dilution Stability
PC-40 Wettability
PC-41 Wet sieve test
PC-42 Degree of Dispersion
PC-43 Suspensibility
PC-44 Spontaneity of Dispersion
PC-45 Flowability
PC-46 Dustiness
PC-47 Attrition resistance
PC-48 Auto Ignition (Autoflamability)
PC-49 Self Ignition (For Solids)
PC-50 Oxidising Property for liquid
PC-51 Volatility
PC-52 Transport worthiness test (Computerised Vibration Table)
PC-53 Fire Point (Pensky Marten Cloased Cup) for higher temp.
PC-54 Photo Stability as per ICH Q1B
PC-55 Metal Analysis (ICP-MS)
PC-56 Persistence Studies in water / soil / plant
PC-57 Residue Analysis
PC-58 Hydroscopicity
PC-59 Adsorption - Desorption Using a Batch Equilibrium Method
PC-60 Hydrolysis
PC-61 Photolysis
PC-62 Soil Microorganisms: Nitrogen Transformation Test
PC-63 Soil Microorganisms: Carbon Transformation Test
PC-64 Ready Biodegradability
PC-65 Degradation/Metabolism
PC-66 Aerobic and Anaerobic Transformation in Soil

Five Batch Studies

  • Pre-screening (preliminary Test)
  • Characterization of sample and ref. impurities
  • Method Development
  • Method Validation
  • Assay
  • Impurity Quantification
  • Residual solvents validation & Quantification
  • Moisture
  • Material Insoluble in Acetone
  • Loss On Drying
  • Sulphated Ash
GC (FID, TCD, ECD, FPD Detectors)
HPLC (UV, RID, PDA Detectors)
GC-MS/MS triple quadrupole with Head space
LC-MS/MS triple quadrupole

Stability Studies

  • Accelerated 14 days 54°C (Optional ±76% RH)
  • Shelf Life (1 year / 2 years)
  • Low Temperature (7 Days)
  • With/without metals (Elevated Temp)